SPURGE FAMILY PLANTS (EUPHORBIACEAE JUSS.) IN INDUSTRY, MEDICINE, DAILY LIFE, AND FOOD PRODUCTION: TRADITIONS, OPPORTUNITIES, AND PROSPECTS
DOI:
https://doi.org/10.32782/naturaljournal.10.2024.1Keywords:
Spurge family, pharmacological properties, medical use, latex, biofuel, food source, daily life useAbstract
The article analyzes scientific literary sources that present the results of complex studies of the spurge family plants from a historical perspective, their botanical discoveries, biological and morphological features, the nature of their biochemical content and related useful properties, and both ancient traditions and modern realities of the plants’ use in evidence-based, alternative, and folk medicine, cosmetology, nutrition, daily life, energy, and industry. As they contain alkanes, triterpenes, phytosterols, and tannins, the Euphorbia plants have an effective and broad therapeutic and improving impact on human health. Their key medicinal properties are anticancer, antipyretic, analgesic, antioxidant, antimicrobial, anti-inflammatory, and anti-arthritic effects. The essential oils of Euphorbia species contain over 80 phytochemicals, including sesquiterpenes and sesquiterpene hydrocarbons. Fresh plant extracts have secondary metabolites: sesquiterpenes, diterpenes, sterols, flavonoids, and other polyphenols. Euphorbiaceous plants play an important role in human life, including daily life, as a source of phytonutrients, rubber, and biofuel. In countries where these plants are endemic ones, they are traditionally used in folk medicine, cooking, daily life, and construction, while their latex is used as a molluscicide, pesticide, or hunting poison. Spurge plants are beneficial and promising, since they are able to use C3 and CAM photosynthesis, though the physiological mechanism of carbon fixation switching is not yet sufficiently studied. Besides, acclimatization and industrial cultivation of these plants – as promising medicinal, food, and biofuel raw materials – requires introductory measures on the territory of Ukraine. Research of biochemical content and dynamics of accumulation of microand macronutrients, as well as study of poisonous properties of the plants and peculiarities of C3 and CAM photosynthesis in the new weather, climate, and soil conditions of Ukraine will be relevant. The new knowledge will expand the scope and effectiveness of the future use of Euphorbiaceae plants as a source of biofuels, biologically active extracts, secondary metabolites, pure compounds, and a component of medicinal products for treating a wide variety of diseases, which will generally contribute to the promotion of human health and longevity.
References
Гайдаржи М.М. Життєві форми і онтоморфогенез сукулентних рослин: автореферат дисертації доктора біологічних наук: 03.00.05 ботаніка. Київський національний університет імені Тараса Шевченка. Київ, 2009. 40 с.
Капустян В.В., Нікітіна В.В., Гайдаржи М.М. Колекція тропічних та субтропічних рослин ботанічного саду імені акад. О.В. Фоміна КНУ імені Тараса Шевченка. Інтродукція рослин. 2004. № 1. С. 27–35.
Лікарські рослини: Енциклопедичний довідник / відп.ред. А.М. Гродзінський. Київ: Видавництво «Українська Енциклопедія» ім. М.П. Бажана. Укр. вироб.-комерц. центр «Олімп», 1992. 544 с.
Лугова О. М., Баданіна В. А. Досвід використання сукулентів при створенні вертикальних садів. “Modern scientific research: achievements, innovations and development prospects”: The 14 th International scientific and practical conference (July 17-19, 2022). MDPC Publishing, Berlin, Germany, 2022. C. 22–29.
Нечитайло В.А., Кучерява Л.Ф. Ботаніка. Вищі рослини. Київ: Фітосоціоцентр, 2000. 432 с.
Огієнко Т.Ю. Мікробіологічне обґрунтування нових засобів на основі лікарських рослин для лікування кандидозу ротової порожнини Дис.докт.філосоії: 221-Стоматологія, 22-Охорона здоров’я. Ів.-Франківськ, 2023. 206 с.
Цебржинський О.І., Орлова Л.Д. Токсичні представники родини молочайних (Euphorbiaceae). Біорізноманіття України в світлі ноосферної концепції академіка В.І. Вернадського: матеріали Всеукраїнської науково-практичної конференції / За загальною редакцією проф. М.В. Гриньової. Полтава: Астрая, 2013. С. 215–219.
Чаговець Р.К., Перцев І.М., Соболєва В.О. Вивчення деяких видів Молочаїв. Фармацевтичний журнал. 1967. № 3. С. 64–67.
Abdelgadir H.A., Johnson S.D., J.Van Staden Pollen viability, pollen germination and pollen tube growth in the biofuel seed crop Jatropha curcas (Euphorbiaceae). South African Journal of Botany. 2012. Vol. 79. P. 132–139. https://doi.org/10.1016/j.sajb.2011.10.005.
Ahmad V.U., Hussain H.B., Bukhari I.A.S., et al. Antinociceptive diterpene from Euphorbia decipiens, Fitoterapia. 2005. Vol. 76. № 2. P. 230–232. https://doi.org/10.1016/j.fitote.2004.12.014.
Aleksandrov M., Maksimova V., Koleva Gudeva L. Review of the Anticancer and Cytotoxic Activity of some Species from Genus Euphorbia. Agric. conspec. sci. 2019. Vol. 84. № 1. Р. 1–5.
Bakhshi G.D., Langade D.G., Desai V.S. Prospective, Open label study of Euphorbia prostrata extract 100 mg in the treatment of bleeding haemorrhoids, Bombay Hospital Journal. 2008. Vol. 50. №4. P. 577–583.
Bani S., Kaul A., Jaggi B.S., Suri K.A., Suri O.P., Sharma O.P. Anti-inflammatory activity of the hydrosoluble fraction of Euphorbia royleana latex. Fitoterapia. 2000. Vol. 71. № 6. P. 655–662. https://doi.org/10.1016/s0367-326x(00)00225-2.
Barla-Demirkoz A., Öztürk M., Kültür Ş.К., Öksüz S. Screening of antioxidant activity of three Euphorbia species from Turkey. Fitoterapia. 2007. № 78 (6). P. 423–425. https://doi.org/10.1016/j.fitote.2007.02.021.
Basma A.A., Zakaria Z., Latha L.Y., Sasidharan S. Antioxidant activity and phytochemical screening of the methanol extracts of Euphorbia hirta L. Asian Pac J Trop Med. 2011. Vol. 4. № 5. P. 386–390. https://doi.org/10.1016/S1995-7645(11)60109-0.
Bolaji A. O., Adeniran I. O., Awotunde A., Akinpelu B.A. Evaluation of Chemical Composition, Anti-inflammatory, Antioxidant and Cytotoxic Potential of Leaf and Root Extracts of Euphorbia graminae. Tropical Journal of Natural Product Research. 2019. Vol. 3. № 6. Р. 201–209. https://doi.org/10.26538/tjnpr/v3i6.4.
Boutoub O., El-Guendouz S., Estevinho L.M., Paula V.B., et al. Antioxidant activity and enzyme inhibitory potential of Euphorbia resinifera and E. officinarum honeys from Morocco and plant aqueous extracts. Environmental Science and Pollution Research. 2021. Vol. 28. Р. 503–517. https://doi.org/10.1007/s11356-020-10489-6.
Calvin M. Energy agriculture. Presented at the Symposium on Controversial Topics in Agricultural and Food Chemistry (12-17 Sept. 1982). American Chemical Society, Kansas City, Mo, U.S.A., 1982. Р. 1–46. [Електронний ресурс]. URL: https://escholarship.org/uc/item/9790c7gt (дата звернення 16.10.2024).
Choudhary R., Tandon R.V. Consumption of functional food and our health concerns. Pakistan Journal of Physioloqy. 2009. Vol. 5. № 1. Р. 73–86. https://doi.org/10.69656/pjp.v5i1.713.
Dabholkar D.A., Kaicker P.K., Diwan R.K. Euphorbia latex-Its chemistry and industrial applications: Part 1. Research and Industry. 1991. Vol. 36. № 2. P. 126–131.
Dias Dileep E., Sarathlal P.S., Ajith Babu T.K. Ayishath Shabna Cnidoscolus Aconitifolius – An Overview. International Journal of Research and Scientific Innovation (IJRSI). 2021. Vol. 8, № 7. P. 22–24. https://doi.org/10.51244/IJRSI.2021.8703.
ESTY. Official website of the company [Електронний ресурс]. URL: https://www.etsy.com/fr/listing/717596633/boutures-de-cactus-crayon-euphorbia (дата звернення 16.10.2024).
González-Stuart A.E., Rivera J.O. Chapter 14-Herbal Weight Loss Supplements: From Dubious Efficacy to Direct Toxicity. Dietary Interventions in Liver Disease ( Foods, Nutrients, and Dietary Supplements): book/ edited by Ronald Ross Watson and Victor R. Preedy. Academic Press, 2019. P. 175–181. https://doi.org/10.1016/B978-0-12-814466-4.00014-8.
Gouri V., Pandey S.C., Joshi D., Pande V., Upreti S., Samant M. Chapter 8 – Natural products as a novel source for antileishmanial drug development. Pathogenesis, Treatment and Prevention of Leishmaniasis. 2021. P. 141–159. https://doi.org/10.1016/B978-0-12-822800-5.00011-1.
Hastilestari B.R., Mudersbach M., Tomala F., et al. Euphorbia tirucalli L.– Comprehensive Characterization of a Drought Tolerant Plant with a Potential as Biofuel Source. PlosONE. 2013. Vol. 8. № 5. е63501. https://doi.org/10.1371/journal.pone.0063501.
Hempen C.-H., Fischer T. III-Herbs that purge and drain. A Materia Medica for Chinese Medicine (Plants, minerals and animal products): book / C.-H. Hempen, T. Fischer. Churchill Livingstone, Elsevier Ltd, 2009. P. 84–109. https://doi.org/10.1016/B978-0-443-10094-9.00006-6.
Jian B., Zhang H., Han C., Liu J. Anti-Cancer Activities of Diterpenoids Derived from Euphorbia fischeriana Steud. Molecules. 2018. Vol. 23. № 2. 387. P. 1–11. https://doi.org/10.3390/molecules23020387.
Johari S., Kumar A. Improving growth and productivity of Euphorbia antisyphilitica: a biofuel plant for semi-arid regions. International Journal of Life science & Pharma Research. 2013. Vol. 3. № 4. P. 20–24.
Krisnawati H., Kallio M., Kanninen M. Aleurites moluccana (L.) Willd.: ecology, silviculture and productivity. CIFOR (Center of International Forestry Research), Bogor, Indonesia, 2011. 11 р.
Kuete V. 22 – Physical, Hematological, and Histopathological Signs of Toxicity Induced by African Medicinal Plants. Toxicological Survey of African Medicinal Plants:book / edited by Victor Kuete. Elsevier, 2014. P. 635–657. https://doi.org/10.1016/B978-0-12-800018-2.00022-4.
Kumar S.A., Harichandan Priyadarshini S.S., Acharya Prangya Paramita, et al. Green synthesis and biochemical characterization of silver nanoparticles by using Euphorbia umbellata leaf extract and analysis of antimicrobial activity against plant Pathogens. GSC Biological and Pharmaceutical Sciences. 2019. Vol. 08. № 02. P. 59–69. https://doi.org/10.30574/gscbps.2019.8.2.0137.
Vikas Kurhekar J. Chapter 4 – Ancient and modern practices in phytomedicine. Preparation of Phytopharmaceuticals for the Management of Disorders. The Development of Nutraceuticals and Traditional Medicine: book / edited by: Chukwuebuka Egbuna, Abhay Prakash Mishra and Megh R. Goyal. Academic Press is an imprint of Elsevier, 2021. P. 55–75. https://doi.org/10.1016/B978-0-12-820284-5.00019-8.
Liu J., Sun Y., Liu L., Yu C. A water-soluble polysaccharide (EFP-AW1) from the alkaline extract of the roots of a traditional Chinese medicine, Euphorbia fischeriana: Fravtion and characterization. Carbohydrate Polymers. 2012. Vol. 88. № 4. P. 1299–1303. https://doi.org/10.1016/j.carbpol.2012.02.004.
Ma Q.-G., Liu W.-Z., Wu X.-Y., Zhou T.-X., Qin G.-W. Diterpenoids from Euphorbia fischeriana. Phytochemistry. 1997. Vol. 44. № 4. P. 663–666. https://doi.org/10.1016/S0031-9422(96)00605-X.
Mali Prashant Y., Panchal Shital S. Euphorbia neriifolia L.: Review on botany, ethnomedicinal uses, phytochemistry and biological activities. Asian Pacific Journal of Tropical Medicine. 2017. Vol. 10. № 5. Р. 430–438. https://doi.org/10.1016/j.apjtm.2017.05.003.
Meise Botanic Garden, Meise, Belgium. Official cite [Електронний ресурс]. URL: https://www.plantentuinmeise.be/en (дата звернення 19.10.2024).
Montaluisa-Mantilla M.S., García-Encina P., Lebrero R., Muñoz R. Botanical filters for the abatement of indoor air pollutants. Chemosphere. 2023. Vol. 345. 140483. Р. 1–15. https://doi.org/10.1016/j.chemosphere.2023.140483.
Mwine J.T. Evaluation of Pesticidal Properties of Euphorbia tirucalli L. (Euphorbiaceae) against Selected Pests. PhD thesis. Belgium: Ghent University, Faculty of Bioscience Engineering, 2011. 145p.
Mwine J., Van Damme P., Hastilestari B.R., Papenbrock J. Euphorbia tirucalli L. (Euphorbiaceae) – The Miracle Tree: Current Status of Knowledge. African Natural Plant Products. 2013. Vol. II: Discoveries and Challenges in Chemistry, Health, and Nutrition. Chapter 1. Р. 3–7. https://doi.org/10.1021/bk-2013-1127.ch001.
Nafiu M.O., Salawu M.O., Kazeem M.I. 21–Antioxidant Activity of African Medicinal Plants. Medicinal Plant Research in Africa. Pharmacology and Chemistry: book / ed. Victor Kuete, Elsevier, 2013. P. 787–803. https://doi.org/10.1016/B978-0-12-405927-6.00021-7.
Nazemiyeh H., Kazemi E.M., Zare K., Jodari M., Nahar L., Sarker S.D. Free radical scavengers from the aerial parts of Euphorbia petiolata. Journal of Natural Medicines. 2010. Vol. 64. Р. 187–190. https://doi.org/10.1007/s11418-009-0382-0.
Nchimbi H.Y. Hydrocarbon yields and stability from Euphorbia tirucalli for quality energy use. Energy Conversion and Management: X. 2021. Vol. 12. 9 р. https://doi.org/10.1016/j.ecmx.2021.100122.
Newton L.E. Euphobias as hedhes. Euphorbia World. Vol. 19. № 2. 2024. P. 11–12.
Nishimura T., Wang L.Y., Kusano K., Kitanaka S. Flavonoids that mimic human ligands from the whole plants of Euphorbia lunulata. Chem Pharm Bull (Tokyo). 2005. Vol. 53. № 3. Р. 305–308. https://doi.org/10.1248/cpb.53.305.
Opeyemi G. Oso, Joseph O. Sunday, Alexander B. Odaibo Temporal modelling of Lymnaea natalensis (Krauss, 1848) in tropical aquatic habitats. Onderstepoort Journal of Veterinary Research. 2023. Vol. 90. № 1. Р. 1–13. https://doi.org/10.4102/ojvr.v90i1.2023.
Özbilgin S., Saltan Citoğlu G. Uses of some Euphorbia species in traditional medicine in Turkey and their biological activities. Turkish Journal of. Pharmaceutical Sciences. 2012. Vol. 9. № 2. P. 241–256.
Patan Shaik Sha Valli Khan, Rajeswari B., Kumar S.P., Terry R.G. Use of Euphorbia sp. (Euphorbiaceae) as biofuel feedstock for semi-arid and arid lands. Biofuels. 2021. Vol. 12. № 5. P. 511–521. https://doi.org/10.1080/17597269.2018.1501637.
Petrovska B.B. Historical review of medicinal plants’ usage. Pharmacognosy Reviews. 2012. Vol. 6. № 11. P. 1–5. https://doi.org/10.4103/0973-7847.95849.
Pharmacopoeia of the PPRC Plant List. Southern Cross University [Електронний ресурс]. URL: https://www.scu.edu.au/analytical-research-laboratory---arl/herbal-authentication/pharmacopoeial-monographs/pharmacopoeia-of-the-pprc-plant-list/ (дата звернення 11.10.2024).
Picato. Withdrawal of the marketing authorisation in the European Union, 2020 [Електронний ресурс]. URL: https://www.ema.europa.eu/en/documents/public-statement/public-statement-picato-withdrawal-marketing-authorisation-european-union_.pdf (дата звернення 11.10.2024).
Podolski-Renić A. The establishing of resistant cancer cell lines as a model for testing of new chemotherapeutics: molecular characterization of resistance developed after continuous treatment with paclitaxel: doctoral dissertation; Faculty of biology University of Belgrade. Belgrade, 2013. 128 р. URL: https://doiserbia.nb.rs/phd/fulltext/BG20130704PODOLSKIRENIC.pdf (дата звернення 16.10.2024).
Poma P., Labbozzetta M., Ramarosandratana A. V., Rosselli S., Tutone M. In vitro modulation of P-glycoprotein activity by Euphorbia intisy Essential oil on acute myeloid leukemia cell line HL-60R. Pharmaceuticals. 2021. Vol. 14. № 2: 111. 20 p. https://doi.org/10.3390/ph14020111.
Ramezani M., Behravan J., Arab M., Amel Farzad S. Antiviral Activity of Euphorbia helioscopia Extract. Journal of Biological Science. 2008. № 8 (4). P. 809–813. https://doi.org/10.3923/jbs.2008.809.813.
Ramsay J.R., Suhrbier A., Aylward J.H., et al. The sap from Euphorbia peplus is effective against human nonmelanoma skin cancers. Then British journal of dermatology. 2011. Viol. 164. №3 Р. 633–636. https://doi.org/10.1111/j.1365-2133.2010.10184.x.
Rizk A.F.M. The chemical constituents and economic plants of the Euphorbiaceae. Botanical Journal of the Linnean Sociaty. 1987. Vol. 94. № 1–2. P. 293–326. https://doi.org/ 10.1111/j.1095-8339.1987.tb01052.x.
Royal Botanic Gardens, Kew. Plants of the World Online [Електронний ресурс]. URL: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:61899-2/images (дата звернення 12.10.2024).
Salehi B., Iriti M., Vitalini S., Antolak H., et al. Euphorbia-Derived Natural Products with Potential for Use in Health Maintenance. Biomolecules. 2019. Vol. 9. № 8:337. P. 1–22. https://doi.org/10. 3390/biom9080337.
Sciencephotolibrery. Scientific Photo Library of France [Електронний ресурс]. URL: https://www.sciencephoto.fr/image/11734639-Sea-spurge-Euphorbia-paralias (дата звернення 12.10.2024).
Scientific opinion on the re-evaluation of candelilla wax (E 902) as a food additive Aguilar Fernando, Crebelli Riccardo, Dusemund Birgit, et al. European Food Safety Autority Journal. 2012. Vol. 10. № 11: 2946. 27 p. doi: 10.2903/j.efsa.2012.2946 [Електронний ресурс]. URL: https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2012.2946 (дата звернення 19.10.2024).
Seidelt R. Some remarks on Euphorbia poissonii Pax. Euphorbia World. 2021. Vol. 17. № 1. P. 46–52.
Shi Q.-W., Su X.-H., Kiyota H. Chemical and pharmacological research of the plants in genus Euphorbia. Chemical Reviews. 2008. Vol. 108. № 10. P. 4295–4327. https://doi.org/10.1021/cr078350s.
Sun Y.-X., Liu J.-C. Chemical constituents and biological activities of Euphorbia fischeriana Steud. Chemistry and Biodiversity. 2011. Vol. 8. № 7. P. 1205–1214. https://doi.org/10.1002/cbdv.201000115.
The Ayurvedic Pharmacopoeia of India Part-I. Volume-I. First edition / Coverment of India. Ministry of Health and Family Welfare. Department of Indian Systems of Medicine Homoeopathy. Delhi, 2001. 171 p. [Електронний ресурс]. URL: https://www.ayurveda.hu/api/API-Vol-1.pdf (дата звернення 15.10.2024).
The Encyclopedia of Succulents [Електронний ресурс]. URL: https://www.llifle.com/Encyclopedia/SUCCULENTS/Family/Euphorbiaceae/28041/Euphorbia_caducifolia (дата звернення 11.10.2024).
The IUCN Red List of Threatened Species. [Електронний ресурс] URL: https://www.iucnredlist.org/ (дата зверення 19.10.2024).
Tiwari S.К., Singh A.K. Biochemical stress response in freshwater fish Channa punctatus induced by aqueous extracts of Euphorbia tirucalli plant. Chemosphere. 2006. Vol. 64. № 1. P. 36–42. https://doi.org/10.1016/j.chemosphere.2005.11.049.
Toyin Y.M., Ajiboye T.O., Akanji M.A. 15- Toxicity and Beneficial Effects of Some African Plants on the Reproductive System. Toxicological Survey of African Medicinal Plants. 2014. P. 445–492. https://doi.org/10.1016/B978-0-12-800018-2.00015-7.
Uchida H., Ohyama K., Suzuki M., et al. Triterpenoid levels are reduced during Euphorbia tirucalli L. callus formation. Plant Biotechnology. 2010. Vol. 27. № 1. Р. 105–109. https://doi.org/10.5511/plantbiotechnology.27.105.
Unusual seeds [Електронний ресурс]. URL: https://unusualseeds.net/euphorbiaceaea-comprehensive-collection-of-stem-succulents/ (дата зверенення 16.10.2024).
«Urbanarbolismo». The official website of the company [Електронний ресурс]. URL: https://www.urbanarbolismo.es/blog/aireacondicionado-vegetal-oficina/ (дата звернення 11.10.2024).
Valente C., Pedro M., Duarte A., et al. Bioactive diterpenoids, a new jatrophane and two ent-abietanes, and other constituents from Euphorbia pubescens. Journal of Natural Products. 2004. Vol. 67. № 5. P. 902–904. https://doi.org/10.1021/np0400048.
Valentine floral creations. The Greek Flouers Portal [Електронний ресурс]. URL: https://www.valentine.gr/linkOfTheMonth_gr-march2016.php (дата звернення 16.10.2024).
Vassiliades G. Note sur les propriétés molluscicides de deux Euphorbiacées: Euphorbia tirucalli et Jatropha curcas. Essais en laboratoire Sénégal. Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux. 1984. Vol. 37. № 1. P. 32–34. https://doi.org/10.19182/remvt.8447.
Wang Z.Y., Liu H.P., Zhang Y.C., Guo L.Q., Li Z.X., Shi X.F. Anticancer potential of Euphorbia helioscopia L. extracts against human cancer cells. The Anatomical Record. 2011. Vol. 295. № 2. P. 223–233. https://doi.org/10.1002/ar.21517.
West African Plants. A photo guide. [Electronic resource] URL: http://www.westafricanplants.senckenberg.de/root/index.php?page_id=14&species=2591# . (дата звернення 16.10.2024).
WFO (2024): World Flora Online. Published on the Internet [Електронний ресурс]. URL: http://www.worldfloraonline.org. (дата звернення 16.10.2024).
Zhang Y., Shi Y., Duan Na, Liu Bing-Bing, Mi Jia. Complete chloroplast genome of Euphorbia tirucalli (Euphorbiaceae), a potential biofuel plant. Mitochondrial DNA Part B: Resources. 2019. Vol. 4. № 1. P. 1973–1974. https://doi.org/10.1080/23802359.2019.1617069.
